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  1. Research

    Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome

    Space travel is associated with continuous low dose rate exposure to high linear energy transfer (LET) radiation. Pathophysiological manifestations after low dose radiation exposure are strongly influenced by non...

    David Casero, Kirandeep Gill, Vijayalakshmi Sridharan, Igor Koturbash, Gregory Nelson, Martin Hauer-Jensen, Marjan Boerma, Jonathan Braun and Amrita K. Cheema

    Microbiome 2017 5:105

    Published on: 18 August 2017

  2. Review

    Schrödinger’s microbes: Tools for distinguishing the living from the dead in microbial ecosystems

    While often obvious for macroscopic organisms, determining whether a microbe is dead or alive is fraught with complications. Fields such as microbial ecology, environmental health, and medical microbiology eac...

    Joanne B. Emerson, Rachel I. Adams, Clarisse M. Betancourt Román, Brandon Brooks, David A. Coil, Katherine Dahlhausen, Holly H. Ganz, Erica M. Hartmann, Tiffany Hsu, Nicholas B. Justice, Ivan G. Paulino-Lima, Julia C. Luongo, Despoina S. Lymperopoulou, Cinta Gomez-Silvan, Brooke Rothschild-Mancinelli, Melike Balk…

    Microbiome 2017 5:86

    Published on: 16 August 2017

  3. Research

    The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment

    The urinary microbiota is similarly complex as the vaginal and penile microbiota, yet its role as a reservoir for pathogens and for recurrent polymicrobial biofilm diseases like bacterial vaginosis (BV) is not...

    Cornelia Gottschick, Zhi-Luo Deng, Marius Vital, Clarissa Masur, Christoph Abels, Dietmar H. Pieper and Irene Wagner-Döbler

    Microbiome 2017 5:99

    Published on: 14 August 2017

  4. Research

    Comparative gut microbiota and resistome profiling of intensive care patients receiving selective digestive tract decontamination and healthy subjects

    The gut microbiota is a reservoir of opportunistic pathogens that can cause life-threatening infections in critically ill patients during their stay in an intensive care unit (ICU). To suppress gut colonizatio...

    Elena Buelow, Teresita d. j. Bello González, Susana Fuentes, Wouter A. A. de Steenhuijsen Piters, Leo Lahti, Jumamurat R. Bayjanov, Eline A. M. Majoor, Johanna C. Braat, Maaike S. M. van Mourik, Evelien A. N. Oostdijk, Rob J. L. Willems, Marc J. M. Bonten, Mark W. J. van Passel, Hauke Smidt and Willem van Schaik

    Microbiome 2017 5:88

    Published on: 14 August 2017

  5. Research

    Community characteristics of the gut microbiomes of competitive cyclists

    Changes in diet and exercise can alter the gut microbiome of humans and mice; however, few studies to date have assessed the microbiomes of highly fit athletes. In this pilot study, we used metagenomic whole g...

    Lauren M. Petersen, Eddy J. Bautista, Hoan Nguyen, Blake M. Hanson, Lei Chen, Sai H. Lek, Erica Sodergren and George M. Weinstock

    Microbiome 2017 5:98

    Published on: 10 August 2017

  6. Research

    Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism

    Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has ...

    Jose A. Caparrós-Martín, Ricky R. Lareu, Joshua P. Ramsay, Jörg Peplies, F. Jerry Reen, Henrietta A. Headlam, Natalie C. Ward, Kevin D. Croft, Philip Newsholme, Jeffery D. Hughes and Fergal O’Gara

    Microbiome 2017 5:95

    Published on: 9 August 2017

  7. Methodology

    Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples

    Sequence-specific PCR is the most common approach for virus identification in diagnostic laboratories. However, as specific PCR only detects pre-defined targets, novel virus strains or viruses not included in ...

    Dagmara W. Lewandowska, Osvaldo Zagordi, Fabienne-Desirée Geissberger, Verena Kufner, Stefan Schmutz, Jürg Böni, Karin J. Metzner, Alexandra Trkola and Michael Huber

    Microbiome 2017 5:94

    Published on: 8 August 2017

  8. Research

    Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni infection in C57BL/6 mice

    Campylobacter jejuni is the leading antecedent infection to the autoimmune neuropathy Guillain-Barré syndrome (GBS), which is accompanied by an autoimmune anti-ganglioside antibody att...

    Phillip T. Brooks, Kelsey A. Brakel, Julia A. Bell, Christopher E. Bejcek, Trey Gilpin, Jean M. Brudvig and Linda S. Mansfield

    Microbiome 2017 5:92

    Published on: 8 August 2017

  9. Research

    Impact of intrapartum antimicrobial prophylaxis upon the intestinal microbiota and the prevalence of antibiotic resistance genes in vaginally delivered full-term neonates

    Disturbances in the early establishment of the intestinal microbiota may produce important implications for the infant’s health and for the risk of disease later on. Different perinatal conditions may be affec...

    Alicja Nogacka, Nuria Salazar, Marta Suárez, Christian Milani, Silvia Arboleya, Gonzalo Solís, Nuria Fernández, Lidia Alaez, Ana M. Hernández-Barranco, Clara G. de los Reyes-Gavilán, Marco Ventura and Miguel Gueimonde

    Microbiome 2017 5:93

    Published on: 8 August 2017

  10. Research

    Virome comparisons in wild-diseased and healthy captive giant pandas

    The giant panda (Ailuropoda melanoleuca) is a vulnerable mammal herbivore living wild in central China. Viral infections have become a potential threat to the health of these endangered animals, but limited infor...

    Wen Zhang, Shixing Yang, Tongling Shan, Rong Hou, Zhijian Liu, Wang Li, Lianghua Guo, Yan Wang, Peng Chen, Xiaochun Wang, Feifei Feng, Hua Wang, Chao Chen, Quan Shen, Chenglin Zhou, Xiuguo Hua…

    Microbiome 2017 5:90

    Published on: 7 August 2017

  11. Research

    Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning

    Human microbiota-associated (HMA) animal models relying on germ-free recipient mice are being used to study the relationship between intestinal microbiota and human disease. However, transfer of microbiota int...

    Christopher Staley, Thomas Kaiser, Lalit K. Beura, Matthew J. Hamilton, Alexa R. Weingarden, Aleh Bobr, Johnthomas Kang, David Masopust, Michael J. Sadowsky and Alexander Khoruts

    Microbiome 2017 5:87

    Published on: 1 August 2017

  12. Research

    Influence of the pneumococcal conjugate vaccines on the temporal variation of pneumococcal carriage and the nasal microbiota in healthy infants: a longitudinal analysis of a case–control study

    Bacterial colonization of the upper airways is a prerequisite for subsequent invasive disease. With the introduction of the 7- and 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13), changes in pneumoc...

    Moana Mika, Josua Maurer, Insa Korten, Aurélie Allemann, Suzanne Aebi, Silvio D. Brugger, Weihong Qi, Urs Frey, Philipp Latzin and Markus Hilty

    Microbiome 2017 5:85

    Published on: 24 July 2017

  13. Research

    Deciphering functional diversification within the lichen microbiota by meta-omics

    Recent evidence of specific bacterial communities extended the traditional concept of fungal-algal lichen symbioses by a further organismal kingdom. Although functional roles were already assigned to dominant ...

    Tomislav Cernava, Armin Erlacher, Ines Aline Aschenbrenner, Lisa Krug, Christian Lassek, Katharina Riedel, Martin Grube and Gabriele Berg

    Microbiome 2017 5:82

    Published on: 19 July 2017

  14. Research

    Whole metagenome profiles of particulates collected from the International Space Station

    The built environment of the International Space Station (ISS) is a highly specialized space in terms of both physical characteristics and habitation requirements. It is unique with respect to conditions of mi...

    Nicholas A. Be, Aram Avila-Herrera, Jonathan E. Allen, Nitin Singh, Aleksandra Checinska Sielaff, Crystal Jaing and Kasthuri Venkateswaran

    Microbiome 2017 5:81

    Published on: 17 July 2017

  15. Research

    Potential and active functions in the gut microbiota of a healthy human cohort

    The study of the gut microbiota (GM) is rapidly moving towards its functional characterization by means of shotgun meta-omics. In this context, there is still no consensus on which microbial functions are cons...

    Alessandro Tanca, Marcello Abbondio, Antonio Palomba, Cristina Fraumene, Valeria Manghina, Francesco Cucca, Edoardo Fiorillo and Sergio Uzzau

    Microbiome 2017 5:79

    Published on: 14 July 2017

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