Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide

Table 1 BBB-associated genes whose expression was upregulated upon exposure of hCMEC/D3 cells to TMAO

Gene	Entrez ID	Description	Log₂ fold change	Category	P_FDR
TFRC	7037	Transferrin receptor	0.23	Transporter proteins	0.054
ABCC4	10257	ATP-binding cassette subfamily C member 4	0.20	Transporter proteins	0.088
ANXA1	301	Annexin A1	0.16	Cell adhesion/junctional proteins/cytoskeletal factors	0.088
CDH2	1000	Cadherin 2	0.31	Cell adhesion/junctional proteins/cytoskeletal factors	0.095

ISSN: 2049-2618