Fig. 3

Scheme for the complexity in diversified mcr-1-bearing plasmids. The mcr-1-carrying plasmids are denoted with circles, in which the mcr-1 gene is highlighted with red arrow. To the best of our knowledge, no less than ten families of plasmids produce the MCR-1 protein. Four types of mcr-1-containing plasmids are labeled in color, corresponding to IncX4 (in green), IncI2 (in purple), IncHI2 (in orange), and the hybrid version of IncI2-IncFIB (in blue), respectively