Table 1 Summary of lung specimens for the evaluation of lung microbiome
| Â | BALF | Lung(i) | Lung(p) | Feces | |||||
|---|---|---|---|---|---|---|---|---|---|
PBS | LPS | PBS | LPS | PBS | LPS | PBS | LPS | ||
Basic description | Clinical availability | Easy | Easy | Hard | Hard | Hard | Hard | Easy | Easy |
Summary of findings (relative to each other) | Bacterial biomass | Low | Medium | Medium | Medium | Medium | Medium | High | High |
Total DNA quality | Dependent | Good | Good | Good | Good | Good | Good | Good | |
Bacterial DNA content | Low | Medium | Medium | High | High | High | —— | —— | |
Results of alpha diversity | Medium | Medium | Medium | Medium | Medium | Medium | Low | Low | |
Variation among biological replicates | Medium | Medium | Medium | Medium | High | High | Low | Low | |
Similarity to biological source community (feces microbiome) | Low | Low | Low | Low | Low | Low | —— | —— | |
Potential ALI biomarker | No | Potential | —— | —— | —— | —— | No | Potential | |