Fig. 2

XYS, as potential antidepressant, alleviated CUMS-induced depression/anxiety -like behaviors, and cognitive impairment. A After 1 week of acclimation, mice were randomly divided into four groups as follows: Control, CUMS, CUMS + XYS, and CUMS + FLX. B Daily body weight changes throughout the entire duration of the study. C Sucrose preference test (SPT). D Open field test(OFT) (Total distance moved). E OFT (Frequency in center zone). F Tail suspension test (TST). G Elevated plus-maze (EPM). H Novel object recognition test (NORT). I Y-maze. J Movement trajectories of mice in OFT, EPM and NORT. Data represent the mean ± SEM (n = 10 per group). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 versus the Control group; ^#P < 0.05, ^##P < 0.01 versus the CUMS group