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Fig. 9 | Microbiome

Fig. 9

From: Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis

Fig. 9

Correlation analysis between the key gut bacteria at the genus level and other measures. A Spearman correlation between the key gut bacteria at the genus level and fetal weight, placental weight, placental efficiency, the activities of T-AOC, MDA, and caspase 3, and the levels of ROS and ATP in cotyledon tissues in CON and BPA pregnant ewes. B Spearman correlation between the key gut bacteria at the genus level and fetal weight, placental weight, placental efficiency, the activities of T-AOC, MDA, and caspase 3, and the levels of ROS and ATP in the placenta in GMT (CON) and GMT (BPA) mice. C Spearman correlation between the key gut bacteria at the genus level and villus weight, VCR, the activities of T-AOC, MDA, and caspase 3, the levels of ROS, ATP and LPS, and VFAs concentration in intestinal tissues in CON and BPA pregnant ewes. D Spearman correlation between the key gut bacteria at the genus level and villus weight, VCR, the activities of T-AOC, MDA, and caspase 3, the levels of ROS, ATP and LPS, and VFAs concentration in intestinal tissues in GMT (CON) and GMT (BPA) mice. “ + ” represents a significantly positive correlation (P < 0.05), “ − ” represents a significantly negative correlation (P < 0.05), and “ns” represents non-significant correlation (P > 0.05). The fetal weight, placental weight, placental efficiency, the activities of T-AOC, MDA, and caspase 3, and the levels of ROS and ATP in cotyledon tissues in CON and BPA pregnant ewes have been published [7]

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