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Fig. 6 | Microbiome

Fig. 6

From: Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis

Fig. 6

Effects of GMT from donor pregnant Hu sheep in CON and BPA groups on the mRNA and protein relative expressions of antioxidation, apoptosis, autophagy, and ERS in maternal ileum in antibiotics-treated mice on day 18 of gestation. A The mRNA abundance of apoptosis-related genes. B Representative immunoblots of apoptosis-related proteins. C Expression levels of apoptosis-related proteins. D The mRNA abundance of antioxidant-related genes. E Representative immunoblots of antioxidant-related proteins. F Expression levels of antioxidant-related proteins. G The mRNA abundance of autophagy-related genes. H Representative immunoblots of autophagy-related proteins. I Expression levels of autophagy-related proteins. J The mRNA abundance of ERS-related genes. K Representative immunoblots of ERS-related proteins. L Expression levels of ERS-related proteins. The data are shown as mean ± SEM, n = 10. Different lowercase letters represent significant differences at P < 0.05. All the relative expression levels of mRNA and protein were normalized to the β-actin and were expressed relative to the GMT (CON) mice (fold of GMT (CON))

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Microbiome

ISSN: 2049-2618

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