Fig. 4

Breed-specific differences involved in SCFA functions in porcine large intestinal enterocytes and Paneth cells. A Volcano plot showing differentially expressed genes between LT and LW piglets in large intestinal epithelial cells. B, C Expression patterns of SCFA transport-related and receptor genes in distinct cell types from the small intestine (B) and large intestine (C), respectively. D KEGG functional enrichment analysis of differently expressed genes in large intestinal epithelial cells between LT and LW piglets at metabolism classification. E, F Expression patterns of β-oxidation (E) and TCA cycle (F) genes in porcine colonic enterocytes between LT and LW piglets. G Scatter plot showing the differentially expressed genes between LT and LW piglets in large intestinal Paneth cells. H Ridge plot showing the expression of LYZ gene in large intestinal Paneth cells between LT and LW piglets. I Dot plot of the SCFA-related receptor gene FFAR2 and HCAR2 in large intestinal Paneth cells between LT and LW piglets