Fig. 4

Differential abundance of genera relative to healthy controls. A Using ANCOM-BC, significant differential log-fold changes between microbes were calculated relative to healthy controls using only baseline values. The model used also evaluated the effect of location and viral outcome. A zero means that there is no significant difference in the genus between cohorts. B Similar to A, however both timepoints were included in the model; therefore, time was added to the model, and we controlled for dependence between samples belonging to the same patient