Fig. 5

FMT-dd caused more severe dyslipidemia under HD after a 4-week recovery period compared with FMT-hd. a Experiment schematic. b The serum TC, TG, HDL-C, and LDL-C levels. c Body weight gain in the last week and Lee’s index level. d H&E and Oil Red O staining digital images. e PCoA plot of OTUs based on the Bray–Curtis similarity among these four groups. f Change in the ratio of Firmicutes to Bacteroidetes. g Change in the Shannon index. h The relative abundance of significantly differential genera in the ND + FMT-hd and ND + FMT-dd groups. i The relative abundance of significantly differential genera in the HD + FMT-hd and HD + FMT-dd groups. All bar plots presented as mean ± standard deviation, evaluated by the unpaired T-test in the GraphPad software. Source data are provided as a Source data file. *p < 0.05, **p < 0.01, ***p < 0.001. Normal control group (NC), antibiotics (AT); fecal microbiota transplantation (FMT); normal diet (ND); high-fat diet (HD); total cholesterol (TC); triglycerides (TG); high-density lipoprotein-cholesterol (HDL-C); low-density lipoprotein-cholesterol (LDL-C); principal coordinate analysis (PCoA); operational taxonomic units (OTU)