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Table 1 KiSMi study participants characteristics

From: Multi-site microbiota alteration is a hallmark of kidney stone formation

Metric

 

Healthy controls

Stone patients

P value

No. enrolled

 

30

83

 

Sex

 

n (%)

n (%)

 
 

Female

11 (37)

32 (39)

 
 

Male

19 (63)

51 (61)

0.99a

Age

 

M (SD)

M (SD)

 
  

55 (11.1)

58 (11.5)

0.28b

BMI

 

M (SD)

M (SD)

 
  

27.6 (4.6)

30.2 (7.0)

0.08c

Other health features

n (%)

n (%)

 

History of stones

0 (0)

70 (84)

<0.0001a

History of UTI

 

9 (30)

43 (52)

0.05a

Smoking status

   
 

Current smoker

0 (0)

12 (14)

 
 

Non-smoker

30 (100)

71 (86)

0.03a

Comorbidities

Cardiac

3 (10)

8 (10)

0.99a

 

Hypertension

8 (27)

32 (39)

0.37a

 

Diabetes

3 (10)

12 (14)

0.75a

 

Hypothyroidism

3 (10)

9 (11)

0.99a

Years since antibiotic use

M (SD)

M (SD)

 
  

5.53 (5.8)

3.4 (4.0)

0.004c

Stone removal procedure

 

n (%)

 
 

PCNL

 

40 (48)

 
 

Ureteroscopy

 

43 (52)

 

Major stone component

   
 

Calcium oxalate

 

40 (77)

 
 

Calcium phosphate

1 (2)

 
 

Uric acid

 

7 (13)

 
 

Struvite

 

3 (6)

 
 

Cystine

 

1(2)

 
 

Unknown (not tested)

31

 
  1. aFisher’s exact test of categorical variables
  2. bUnpaired two-tailed t-test for normally distributed continuous variables
  3. cMann-Whitney U test for non-normally distributed continuous variables