Fig. 1
From: Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles
Extracellular vesicles of maternal fecal samples (FE EVs) show a wider size distribution as compared to amniotic fluid-derived extracellular vesicles (AM EVs). Representative size distribution of EVs derived from the amniotic fluid and feces in nanoparticle tracking analysis (NTA) (A). Analysis of the EV size as represented by the mean and mode, with error bars indicating the standard deviation, n = 26 amniotic fluid and n = 25 fecal samples, each dot representing one sample, *p < 0.05 and ***p < 0.001 in a paired, two-tailed t-test (B). The size distribution of EVs represented as the mean of the diameter 10th percentile (D10), diameter 50th percentile (D50), and diameter 90th percentile (D90) values corresponding to different percentages of the EV population under the given diameter, with error bars indicating standard deviation, n = 26 amniotic fluid and n = 25 fecal samples, *p < 0.05 and ***p < 0.001 in the paired, two-tailed t-test (C). Representative transmission electron micrographs of the amniotic fluid and fecal EVs (D)