Fig. 4

Inter-kingdom network and keystone species. a Network of the SparCC correlation between the fungal and bacterial taxonomic composition at the species level (FDR < 0.01). Each node shows a unique microbial species, each edge showing the SparCC correlation between the two nodes linked. The edges connecting the nodes represent significant correlations (FDR < 0.001). The color of the nodes represents the kingdom of the specific species and highlights the keystone species. The size of the nodes represents the node degrees for each node. The color of the edges represents the symbol of the correlation, and the width of the edges represents the intensity of the correlation. b Degree distribution of the network following a scale-free distribution. c Candida albicans, one of the fungal species that has a high node degree and the highest betweenness centrality