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Table 1 Characteristics of study participants

From: Integrating compositional and functional content to describe vaginal microbiomes in health and disease

Categories

Number of women with category-specific data (N = 1024)

Number of samples with category-specific data (N = 1890)

Metagenomic data source

1017

1890

 UMB-HMP

124 (12.2%)

515 (27.2%)

 Li et al.

44 (4.3%)

44 (2.3%)

 LSVF

585 (57.5%)

653 (34.6%)

 NIH-HMP

76 (7.5%)

174 (9.2%)

 VMRC

40 (3.9%)

162 (8.6%)

 VIRGO

148 (14.6%)

342 (18.1%)

Age (years)

897

1623

 15–20

283 (31.5%)

410 (25.3%)

 21–25

229 (25.5%)

436 (26.9%)

 26–30

188 (21.0%)

362 (22.3%)

 31–35

102 (11.4%)

223 (13.7%)

 36–40

65 (7.2%)

125 (7.7%)

 41–45

30 (3.3%)

67 (4.1%)

Race

858

1441

 Asian

54 (6.3%)

66 (4.6%)

 Black or African-American

610 (71.1%)

968 (67.2%)

 Hispanic or Latino

19 (2.2%)

47 (3.3%)

 Other

6 (0.7%)

9 (0.6%)

 White or Caucasian

169 (19.7%)

351 (24.4%)

Nugent category

968

1623

 0–3

469 (48.5%)

931 (57.4%)

 4–6

194 (20.0%)

255 (15.7%)

 7–10

305 (31.5%)

437 (26.9%)

Vaginal pH category

874

1362

 Low (pH < 4.5)

273 (31.2%)

491 (36.0%)

 High (pH ≥ 4.5)

601 (68.8%)

871 (64.0%)

Amsel-BV diagnosis

627

673

 Positive

289 (46.1%)

308 (45.8%)

 Negative

338 (53.9%)

365 (54.2%)

Symptomatic Amsel-BV

289

308

 Asymptomatic

253 (87.5%)

271 (88.0%)

 Symptomatic

36 (12.5%)

37 (12.0%)

  1. For each data category (age, race, etc.), the total number of women and samples are noted. Percentages represent the proportions of women or samples within each category. Some women contributed multiple samples
  2. Vaginal Non-redundant Gene Database (VIRGO, virgo.igs.umaryland.edu) [29], the University of Maryland Baltimore Human Microbiome Project (UMB-HMP, PRJNA208535, PRJNA575586, PRJNA797778), the National Institutes of Health Human Microbiome Project (NIH-HMP, phs000228), Li et al. [31] (PRJEB24147), the Longitudinal Study of Vaginal Flora and Incident STI (LSVF, dbGaP project phs002367)