Skip to main content
Fig. 2 | Microbiome

Fig. 2

From: Surgery-induced gut microbial dysbiosis promotes cognitive impairment via regulation of intestinal function and the metabolite palmitic amide

Fig. 2

Surgery causes brain pathological changes in aged mice. A Immunofluorescence staining was used to detect the expression level of the microglial marker IBA1 (green) and astrocyte marker GFAP (red) in the hippocampus of mouse brain tissues in each group. B Correlation with A, the fluorescence intensity of IBA1 and GFAP in the hippocampus of the mouse brain tissues in each group was calculated. C Confocal laser microscopy magnified the microglia positively expressing IBA1 in the hippocampus of mouse brain tissues in each group. D Correlation with C, the number of branches of microglia expressing IBA1 positively in the hippocampus of the mouse brain tissues of each group was calculated. E Golgi staining was used to detect morphological changes in neurons and dendrites in the hippocampus of mice in each group. F Correlation with E, the length of the spines in each group of mouse neurons under the same magnification. **P < 0.01, ****P < 0.0001, ns means no significant

Back to article page

Microbiome

ISSN: 2049-2618

Contact us