Fig. 6
From: Oral pathogens exacerbate Parkinson’s disease by promoting Th1 cell infiltration in mice
Neutralization of IFNγ alleviates dopaminergic neuronal loss in MPTP + LIP-mix treated mice. A Schematic illustration of the experimental procedure. Anti-IFNγ, IFNγ-neutralizing antibody. B Western blotting analysis of TH in ST. C-D) Representative immunohistochemical staining (C) and quantification (D) of TH-positive fibers in ST. E–F Representative immunohistochemical staining (E) and quantification (F) of TH-positive neurons in SN. n = 5:5:5:5. Scale bar: 200 μm. Values are expressed as mean ± SEM. Two-way ANOVA followed by Tukey’s multiple comparisons test was used for statistical analysis. ns, not significant. *P < 0.05, **P < 0.01