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Fig. 2 | Microbiome

Fig. 2

From: Integrated multi-omics analysis reveals the positive leverage of citrus flavonoids on hindgut microbiota and host homeostasis by modulating sphingolipid metabolism in mid-lactation dairy cows consuming a high-starch diet

Fig. 2

Diversity and composition of the feces bacterial community of dairy cows. A Alpha diversity indices. B Beta diversity based on the principal coordinate analysis (PCoA) using the weighted UniFrac distance. C Relative abundance of phyla between two groups. D Relative abundance of genera between two groups. E Analysis of differences in the microbial taxa at the genus level shown by linear discriminant analysis (LDA) effect size (LEfSe) and heatmap of differentially abundant genera. The blue color represents less abundant, red represents the more abundant (CFE vs CON). F Correlation network of differential genera. Red, positive correlations; blue, negative correlations. Only the genera connections (correlation values >|0.6|, P < 0.05) are retained. G Heatmap of Spearman’s correlation between fecal genera and fecal or serum biochemical parameters. Red, positive correlations; blue, negative correlations. *P < 0.05, **P < 0.01. CON, control; CFE, citrus flavonoid extract; ANOSIM, analysis of similarities; ALT, alanine aminotransferase; Hp, haptoglobin; LPS, lipopolysaccharide; LBP, LPS-binding protein

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