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Fig. 6 | Microbiome

Fig. 6

From: Blocked conversion of Lactobacillus johnsonii derived acetate to butyrate mediates copper-induced epithelial barrier damage in a pig model

Fig. 6

SCFAs and microbial community following acetate and butyrate intervention. A Concentrations of colonic lactate, acetate, propionate, and butyrate. B PCoA of the colonic microbiome based on weighted the UniFrac distance metrics. Significance between community structure was evaluated by PERMANOVA. C The most differential taxa at the genus level were exhibited by LEfSe analysis. D The mean relative abundance of top 30 genera in the colonic digesta of mice on day 28. E Lachnospiraceae NK4A136 group and its association with L. johnsonii within the colon. F Butyrate concentration and its association with relative abundance of Lachnospiraceae NK4A136 group within the colonic digesta of mice on day 28. CF, fecal bacterial suspension of pigs in copper-free group. CR, fecal bacterial suspension of pigs in copper-rich group. CR-Lj, fecal bacterial suspension of pigs in copper-rich group with L. johnsonii. CR-A, fecal bacterial suspension of pigs in copper-rich group with acetate. CR-B, fecal bacterial suspension of pigs in copper-rich group with butyrate. Values are shown as mean and error bars represent SEM. One-way ANOVA with Tukey’s test. Statistically significant differences are shown with letters; p < 0.05

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Microbiome

ISSN: 2049-2618

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