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Fig. 4 | Microbiome

Fig. 4

From: Blocked conversion of Lactobacillus johnsonii derived acetate to butyrate mediates copper-induced epithelial barrier damage in a pig model

Fig. 4

SCFAs and microbial community following L. johnsonii administration. A PCoA of the colonic microbiome based on weighted the UniFrac distance metrics. Significance between community structure was evaluated by PERMANOVA. B The mean relative abundance of top 30 genera in the colon. The most differential taxa at genus level were exhibited by LEfSe analysis; CR group versus CF group (C), CR group versus CR-Lj group (D). E Concentrations of colonic lactate, acetate, propionate, and butyrate. F SCFA (acetate, butyrate) concentration and its association with copy number of L. johnsonii within the colonic digesta of mice on day 28. CF, fecal bacterial suspension of pigs in copper-free group. CR, fecal bacterial suspension of pigs in copper-rich group. CR-Lj, fecal bacterial suspension of pigs in copper-rich group with L. johnsonii. Values are shown as mean and error bars represent SEM. One-way ANOVA with Tukey’s test, CR group versus other groups. *p < 0.05, ***p < 0.001

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Microbiome

ISSN: 2049-2618

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