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Fig. 2 | Microbiome

Fig. 2

From: Gut microbiota of old mice worsens neurological outcome after brain ischemia via increased valeric acid and IL-17 in the blood

Fig. 2

Aging-dependent worsening of neurological outcome and heightened inflammatory response after brain ischemia. Old mice (18 months old) or young mice (8 weeks old) were subjected to 120-min MCAO. Their neurological outcome was evaluated, and blood was collected 24 h after MCAO. A representative brain slice images after 2,3,5-triphenyltetrazolium chloride staining, B infarct volume, C neurological deficit scores, D performance on rotarod, E IL-17 concentrations in the blood, F IL-1β concentrations in the blood, G IL-6 concentrations in the blood, and H IL-10 concentrations in the blood. Parametric results in normal distribution are in mean ± S.E.M. (panels B and D to H) and other results that are nonparametric data or parametric data in non-normal distribution are presented as median with interquartile range (panel C). Data of each individual animal is also presented (n = 8–12)

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Microbiome

ISSN: 2049-2618

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