Fig. 2

Oropharynx and nasopharynx microbiota profiles. Dendrogram showing the clusters identified by hierarchical cluster analysis performed on the Euclidean distance of the centered log-ratio transformed data (Aitchison distance). The gray lines surrounding clades represent the clusters identified by the Calinski and Harabasz index. Clusters inside the gray rectangle are the oropharyngeal clusters merged after cross-validation by random forest analysis. Bars below the dendrogram indicate clusters, samples in which pneumococcus was identified, and sampling site