Table 2 Annotation of the GWAS results on SCFAs

Propionate

0.183

4

29,414,391

-

29,417,189

Chr4:29,417,189:G > A

MAML3

Notch signaling pathway

MGST2 (50 k upstream)

Glutathione metabolism

Metabolism of xenobiotics

Drug metabolism Metabolic pathways

SETD7 (70 k upstream)

Lysine degradation

Metabolic pathways

FoxO signaling pathway

Butyrate

0.242

2

-

Chr2:11,072,248:C > T

NA

7

-

Chr7:1,661,848:G > A

lnc_RNA

Valerate

0.389

6

28,682,597

-

28,802,237

Chr6:28,682,597:T > C

TDRD1

6

Chr6:28,792,315:G > A

ABLIM1

6

Chr6:28,721,051:A > G

AFAP1L2

Isovalerate

0.401

6

28,682,597

-

28,802,237

Chr6:28,682,597:T > A

TDRD1

6

Chr6:28,721,051:A > G

AFAP1L2