Fig. 4
From: Recipient-independent, high-accuracy FMT-response prediction and optimization in mice and humans
Clinical predictions post-FMT and engraftment success vs improvement in recipients clinical symptoms post-FMT. A Distribution of success vs failure given a certain donor over 6 clinical cohorts. The x-axis represents the percent of success given a certain donor, the y-axis represents the frequency. B, C iMic predictions of improvement in recipients’ clinical symptoms in WGS cohorts (B) and IBD 16S cohort (C). In the IBD cohort, we also compare our predictions to state-of-the-art (SOA) reported predictions in [37] D–H Swarm plots of predicted recipients’ Shannon of the subjects their FMT succeeded and the subjects their FMT failed over different clinical conditions IBD (D), IBS (E), melanoma (F), UC (G), and antibiotics resistance (AR) (H). A two-sided T-test was applied between the success and failure groups of each cohort (\(*\) \(p<0.05\),\(**\) \(p<0.01\), \(***\) \(p<0.001\))