Table 1 Genes and respective protein families (Pfam IDs) for which the G. fascicularis-associated bacterial genomes were interrogated. Pfam IDs of interest were chosen based on their known involvement in ROS and RNS-scavenging via enzymatic activity or the production of key antioxidants, translocation of sugars via bidirectional sugar transporters and establishment and promotion of the coral-bacteria symbiosis through eukaryotic repeat proteins. Pfam IDs of interest were sourced from the Uniprot database (https://www.uniprot.org/uniprotkb). To annotate Pfam IDs of interest Interproscan 5.55 v88.0 [60] was used

ROS-scavenging

Glutathione synthesis

gshAB

PF04262, PF02955, PF02951

Zeaxanthin and β-carotene synthesis

crtZ, crtY

PF04116, PF18916

Mannitol synthesis

mtlD, mtlK

PF01232, PF08125

Superoxide scavenging (Superoxide dismutase)

SOD MnFe

PF00081, PF2777

Dimethyl sulphide synthesis

dddQ, dddY, dddL

PF16867

Dimethylsulfoniopropionate synthesis

dsyB

PF00891, PF16864

RNS-scavenging

Peroxynitrite reduction

ahpC

PF10417

Nitric oxide reduction

hmp

PF00970, PF00175, PF00042

Nitric oxide reduction

norB, norC

PF00115, PF00034

Nitrous oxide reduction

nosZ

PF18764, PF18793

Carbon translocation

Bidirectional sugar transport

SemiSWEET protein

PF04193, PF03083

Symbiosis establishment/promotion

Eukaryote-like repeat proteins

Ankyrin-repeat proteins

PF00023, PF12796, PF13637, PF13857

WD40-repeat proteins

PF00400, PF07676