Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O1

Table 5 Effect of ASP on tight junction protein and lymphocyte factor in calf ileum

Items	NC	MC	0.5 mg/kg CIP	2.50 g/kg ASP
ZO-1, ng/0.2 g	130.36 ± 6.50^b	110.0 ± 6.83^c	133.81 ± 10.42^b	156.90 ± 11.97^a
Occludin, ng/0.2 g	707.23 ± 16.37^b	636.56 ± 20.91^b	650.98 ± 30.90^b	1062.52 ± 97.94^a
Claudin-1, pg/0.2 g	220.28 ± 2.03^b	214.32 ± 5.28^b	211.51 ± 6.34^b	232.04 ± 3.17^a
CD4⁺, ng/0.2 g	72.39 ± 4.35^a	59.03 ± 3.80^b	70.32 ± 1.04^a	73.39 ± 4.80^a
CD8⁺, ng/0.2 g	28.50 ± 2.84^ab	32.19 ± 2.67^a	25.75 ± 1.21^b	25.20 ± 3.11^b
CD11c⁺, ng/0.2 g	45.42 ± 0.54^ab	43.61 ± 1.79^ab	47.50 ± 1.17^a	37.31 ± 0.21^b

^a,b,cMeans bearing different superscripts in the same row differ significantly (P < 0.05)

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