Table 2 Basic characteristics of 28 OSCC patients analyzed before and after treatment

Sex^a, male (%)

15 (54%)

Mean age, years (SD)

65.7 (10.3)

69.8 (10.3)

Smokers (%)

11 (39%)

Alcohol users (%)

20 (71%)

Edentate (%)

1 (4%)

4 (14%)

NS

Mean SFR, ml/min (SD)

1.1 (0.6)

0.8 (0.6)

p = 0.0008

 Dry mouth, SFR < 0.5 ml/min (%)

4 (14%)

10 (36%)

NS

Mean concertation of bacterial DNA, 16S qPCR, ng/μl (SD)

2.7 (2.3)

2.3 (2.7)

NS

Candidiasis^b (%)

11 (39%)

19 (68%)

p = 0.03

 Mean Candida concentration, log10[CFU/ml] (SD)

2.3 (1.3)

2.9 (1.3)

NS

 Mean concentration of yeasts, 28S qPCR, ng/μl (SD)

0.0049 (0.008)

0.0093 (0.02)

NS

Tumor class ^c

 T1 (%)

19 (68%)

 T2–T4 (%)

9 (32%)

Stage^c

 I–II (%)

18 (64%)

 III–IV (%)

10 (36%)

Treatment

 Excision with direct wound closure (%)

5 (28%)

 Reconstructive surgery (%)

11 (39%)

 Reconstructive surgery + radiation therapy (%)

11 (39%)

 Reconstructive surgery + chemoradiation therapy (%)

1 (4%)