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Fig. 3 | Microbiome

Fig. 3

From: Early-life prophylactic antibiotic treatment disturbs the stability of the gut microbiota and increases susceptibility to H9N2 AIV in chicks

Fig. 3

Changes in the diversity and composition of gut microbiota in chickens with time in the short-term antibiotic treatment trial. A Boxplot showing the Shannon diversity index of gut microbiota in chickens with time. Different red lowercase letters denote statistical significance (P < 0.05, ANOVA, Tukey HSD test). B Principal coordinate analysis (PCoA) of the bacterial communities based on Bray–Curtis distances for the pre-infection samples from the SAT trial. Below and left boxplots show the overall distribution of PCoA 1 and PCoA 2 scores within each group, and the red asterisk (*) indicates significant difference compared to the NAB-S group (*P < 0.05, **P < 0.01, Wilcoxon rank-sum test). C Number of bacterial genera with significant changes in each group after viral infection (ANOVA, Tukey HSD test). D Variation of the relative abundance of Escherichia-Shigella in each group. Data are represented as mean ± SE. Different lowercase letters denote statistical significance (P < 0.05, ANOVA, Tukey HSD test)

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