Fig. 3From: Early-life prophylactic antibiotic treatment disturbs the stability of the gut microbiota and increases susceptibility to H9N2 AIV in chicksChanges in the diversity and composition of gut microbiota in chickens with time in the short-term antibiotic treatment trial. A Boxplot showing the Shannon diversity index of gut microbiota in chickens with time. Different red lowercase letters denote statistical significance (P < 0.05, ANOVA, Tukey HSD test). B Principal coordinate analysis (PCoA) of the bacterial communities based on Bray–Curtis distances for the pre-infection samples from the SAT trial. Below and left boxplots show the overall distribution of PCoA 1 and PCoA 2 scores within each group, and the red asterisk (*) indicates significant difference compared to the NAB-S group (*P < 0.05, **P < 0.01, Wilcoxon rank-sum test). C Number of bacterial genera with significant changes in each group after viral infection (ANOVA, Tukey HSD test). D Variation of the relative abundance of Escherichia-Shigella in each group. Data are represented as mean ± SE. Different lowercase letters denote statistical significance (P < 0.05, ANOVA, Tukey HSD test)Back to article page