Fig. 7

Acute OFS treatment alters the small intestinal microbiota. Rats were fed a HF-diet for 6 weeks and a subset was supplemented with OFS in drinking water for 3 days. Principal coordinate analysis (PCoA) of weighted UniFrac distances of the a USI and b LSI microbial profiles between HF (red) and HF-OFS (blue) rats. Axes indicate the percentage of variation explained by the plotted principal coordinates. Diverging bar plots show significant Log-Fold Change of bacterial genera in HF-OFS rats compared to HF rats in the c USI and d LSI. Different taxonomic annotation with the same genus label are appended with numbers in order to separate the values. The feature labels (y-axis labels) in each plot represent the most specific named taxonomic level describing the feature. Feature identifiers that are duplicated represent instances of a duplicated taxonomic name at the taxonomic level displayed in the feature identifier. The number following the feature identifiers in these cases is used only for unique identification in the current figure. It is not taxonomically meaningful. e Relative frequency of Bifidobacterium pseudolongum in the USI and LSI