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Fig. 6 | Microbiome

Fig. 6

From: Microbiome and tryptophan metabolomics analysis in adolescent depression: roles of the gut microbiota in the regulation of tryptophan-derived neurotransmitters and behaviors in human and mice

Fig. 6

FMT from healthy volunteers improved the synaptic plasticity and glial activities induced by CRS in mouse brains. A, B Colocalization of F-actin and Drebrin along with the respective coefficient analysis. C, D Colocalization of Synapsin1 and PSD95 along with the respective coefficient analysis. E Protein expression of Drebrin, PSD95, and Syn1 along with their statistical graphs. F Protein expression of GFAP and Iba1 along with their statistical graphs. G, H MFI of GFAP and their statistical graphs. I, J MFI of Iba1 and their statistical graphs. Scale bar 50 μm. Data were displayed as mean ± SEM. Significant differences were determined via one-way ANOVA and Tukey’s multiple comparison procedure. *p < 0.05, **p < 0.01, ***p < 0.001 vs. the CTR group; #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 vs. the CRS group; &p < 0.05, &&p < 0.01, &&&p < 0.001 vs. the CRS + HC-tr group

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Microbiome

ISSN: 2049-2618

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