Fig. 3
Microbial QTL. Outer ring to inner ring: Significant QTL in the QTL model (black) for ASV associated with the genus Coriobacteriaceae UCG-002 on Chr 8 at Asvq1, the genus Enterohabdus on Chr 8 at Asvq2, multiple uncultured bacterium from the Muribaculaceae family on Chr 14 at Asvq3 and Chr 17 at Asvq4 and Asvq5, the genus Alistipes on Chr 12 at Asvq6, the genus Rikenella on Chr 1 at Asvq7, the genus Rikenellaceae RC9 Gut Group on Chr 11 at Asvq8, the genus Streptococcus on Chr 8 at Asvq9 and Asvq10, the genus GCA-900066575 on Chr 9 at Asvq11, the genus Lachnoclostridium on Chr 1 at Asvq12 and Chr 13 at Asvq13, the genus Romboutsia on Chr 5 at Asvq14 and Chr 13 at Asvq15, the genus Ruminiclostridium 9 on Chr 1 at Asvq16, and the genus Bilophila on Chr 1 at Asvq17 and Chr 9 at Asvq18. Significant QTL in the diet specific model (blue) for ASV associated with multiple uncultured bacterium from the Muribaculaceae family on Chr 13 at Asvq19 and Asvq20, Chr 14 at Asvq21 and Asvq22, and Chr 17 at Asvq5, the genus Rikenelleceae RC9 Gut Group on Chr 16 at Asvq23, the genus Parabacteroides on Chr 16 at Asvq24, the genus Lactobacillus on Chr 8 at Asvq25, multiple ASV from the Streptococcus genus on Chr 8 at Asvq9, and Asvq10, the uncultured genera from the family of Clostridiales vadinBB60 group on Chr 6 at Asvq26, and the Lachnospiraceae family on Chr 1 at Asvq27. A single significant QTL in the sex specific model (orange) for the genus Alistipes on Chr 13 at Asvq28; Previously identified QTL for metabolic traits and diversity measures in the combined model (black) and diet specific model (blue). Fat mass gain during the feeding trial on Chr 1 at Fmgq1, along with serum HDL cholesterol concentration after the feeding trial on Chr 1 at Hdlq1, Bray–Curtis and Jaccard measures of beta diversity at Bcpc2q and Jpc2q. Unweighted unifraction on Chr 8 at Uufpc2q, and weighted unifraction on Chr 16 at Wufpc1q. Fmgq1, Hdlq1, Bcpc2q, and Jpc2q overlap the same region of the genome as Asvq7, Asvq16, and Asvq17 for uncultured Rikenella, Ruminiclostridium, and uncultured Bilophila. Wufpc1q overlaps the same region of the genome for Asvq23 and Asvq24 for Rikenelleceae RC9 gut group and Parabacteroides