Fig. 4

Metabolic pathways associated with fungal enterotypes. a The fungal pathways enriched in different fungal enterotypes (bottom) and associated fungal genera (top). Log(FC) denotes log-transformed fold change of the average relative abundance of the pathway within respective fungal enterotypes relative to that of the others. Asterisks denote the statistical significance of multiple testing corrected Pearson correlation tests (top) and multiple testing corrected Wilcoxon rank-sum tests (bottom): *adjusted p < 0.05, **adjusted p < 0.01, ***adjusted p < 0.001. Stars mark the metabolic pathways involved in carbohydrate degradation. b The relationship between the fungi-contributed pathway PWY-7279 and age. c The relationship between the fungi-contributed pathway PWY-2723 and BMI