Fig. 1

Composition and diversity of the human gut mycobiome across studies and geographic sites. a Geographic distribution of study populations and associated fungal enterotypes, where the datasets are sequenced with either ITS1 or ITS2 barcodes. b Genus-level gut mycobiome composition across the three continents (North America, Europe, and Asia). c Cumulative curves of the number of detected genera according to the number of sequenced samples from different study populations. d The distribution of fungal Shannon diversity across study populations. The Venn diagram shows the number of fungal genera detected by ITS1- and ITS2- based amplification. e, The correlation between the Shannon index of bacteria and that of fungi in the Zuo et al. [22] cohort, with shaded region representing 95% confidence intervals of the linear regression