Fig. 5From: Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1Abcb1a expression level is microbiota-dependent in the small intestine. Comparison of the mRNA expression of Abcb1a in the proximal, median and distal small intestine; in the colon; and in the liver of conventionalized (CVZ) and germ-free (GF) mice (n = 4–5/group). ***p < 0.001 and **p < 0.01Back to article page