Fig. 2
From: Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1
Faecal microbiota composition evolves upon tacrolimus (TAC) treatment. A, B Principal component analysis (PCA) of the relative abundances of taxa in control (CTL) and TAC-treated mice. Data are presented for the genus A and the family B taxonomic levels before and after 2 and 5 days of oral gavage. C, D Relative abundance of genera (C) and families (D) identified as significantly impacted by TAC treatment (n = 7–8/group). **p < 0.01, *p < 0.05 (Mann–Whitney, CTL vs TAC). #p < 0.05 (Friedman test with Dunn post hoc test, TAC repeated measures)