Fig. 1
From: Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1
Determination of tacrolimus (TAC) pharmacokinetics (PK) profile in mice. A Blood concentration of TAC according to the dose (n = 10/group). B TAC blood concentration–time curve at the selected dose of 3 mg/kg (24 mice providing each 3 measurements, n = 12 measurements/time points covering 6-time points, as described in the Supplementary Methods)