Skip to main content
Fig. 2 | Microbiome

Fig. 2

From: A systematically biosynthetic investigation of lactic acid bacteria reveals diverse antagonistic bacteriocins that potentially shape the human microbiome

Fig. 2

LAB BGCs are diverse and taxa-specific. a The figure shows the clustering of 129,878 biosynthetic gene clusters (BGCs) into 2,849 gene cluster families (GCFs) and 112 gene cluster clans (GCCs). The innermost dendrogram displays the hierarchical clustering of 112 GCCs based on their average cosine distance to MIBiG BGCs. The next outer layer illustrates the proportion of different genera, with genera having less than 200 genomes grouped into "Others". The subsequent layer represents the proportion of BGC classes, with the size of the points being proportionate to their representation. The two outer layers refer to log2-transformed BGC count and average distance to MiBiG BGCs. The triangles denote clans dominated by particular class II bacteriocins-related domains (proportion > 80% in one clan). The predominant bacteriocins-related domains are shown in Supplementary Fig. 10. b The bar plot shows the number of GCFs present in different genera (left), species (medial), and genomes (right)

Back to article page