Table 1 Significant genes identified from the first-stage gene-level analysis of the HCHS/SOL data, using the PC-adjusted KRV (\(\alpha = 2.6 \times 10^{-6}\))
Microbiome kernel | Significant genes | Number of common variants | P-value |
|---|---|---|---|
Bray-Curtis | C1orf141 | 484 | \(1.1 \times 10^{-6}\) |
| Â | IL23R | 284 | \(2.4 \times 10^{-6}\) |
Unweighted UniFrac | MTMR12 | 174 | \(6.5 \times 10^{-8}\) |
| Â | ZFR | 288 | \(2.5 \times 10^{-9}\) |
CLR-linear | MTMR12 | 174 | \(1.7 \times 10^{-6}\) |