Fig. 1

Genomic analyses reveal new lanthipeptides from archaea. a Phylogenetic analysis of LanMs reveals the novelty of archaeal class II lanthipeptide LanMs. The red branch represents archaeal LanMs, and the black branch represents bacterial LanMs used as the outgroups. b Sequence similarity network (SSN) of precursor peptides from archaea (purple) and bacteria (green). c The SSN of archaeal class II lanthipeptide precursors (red and blue) identified in this study and bioinformatically predicted precursors in previous studies (black). The blue and red nodes represent the precursors identical to previous studies and unique ones identified in this study, respectively. Characterized Alnα and Alnβ in this study are highlighted in big size