Fig. 9From: Over supplementation with vitamin B12 alters microbe-host interactions in the gut leading to accelerated Citrobacter rodentium colonization and pathogenesis in miceIn vitro competition assay of C. rodentium and B. thetaiotaomicron under physiological relevant concentrations of cyanocobalamin. Cyanocobalamin alone was unable to directly alter C. rodentium growth or virulence. a Enumeration of C. rodentium and B. thetaiotaomicron grown in competition for 6 h anaerobically and b of C. rodentium grown alone. Expression of gene related to virulence (Ler, Tir, and EspA) did not differ between treatments when C. rodentium was grown in c competition or d alone at different concentrations of cyanocobalamin (n = 6; P < 0.05)Back to article page