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Fig. 8 | Microbiome

Fig. 8

From: Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization

Fig. 8

Effect of macrophage depletion on UDCA-mediated alleviation of intestinal inflammation in LBW-FMT mice (n = 8). A Schematic outline of the experimental design. B Body weight changes. C Representative H&E staining (×40 magnification) of the colon sections. D Histology score. E The mRNA expression levels of proinflammatory cytokines (IL-6, TNF-α, and IL-1β) and F bile acid receptors in the colon. Data are presented as means ± SEM. *P < 0.05, **P < 0.01. LBW-FMT, mice transplanted with the feces of LBW piglets; NBW-FMT, mice transplanted with the feces of NBW piglets

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Microbiome

ISSN: 2049-2618

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