Fig. 6
L. reuteri improves metabolic disorders in DIO mice treated with CQA. HFD-fed mice were treated twice per week with L. reuteri + CQA (1 × 108 CFU bacteria, 50 mg/kg CQA) by oral gavage for 5 weeks. a Schematic diagram of the L. reuteri supplementation in combination with CQA. b Body weight change. c Daily food intake. d Adipose index. e ITT and AUC. f Serum triglyceride. g Serum T-CHO. h Hepatic triglyceride. i Hepatic T-CHO. j Representative Oil red O staining of liver sections, scale bar: 50 μm. Lipids were stained positive (red color) with Oil red O and quantified by Image J software. k Core temperature. l Relative mRNA expression of thermogenic genes in iWAT. m Representative UCP1 staining of iWAT sections, scale bar: 50 μm. n = 8/group. Data are presented as mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001. ns means not statistically significant