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Fig. 5 | Microbiome

Fig. 5

From: Human microbiota drives hospital-associated antimicrobial resistance dissemination in the urban environment and mirrors patient case rates

Fig. 5

Geospatial dissemination of outbreak carbapenem-resistance plasmid depends on urban sewage infrastructure. A Boxplot showing a statistically significant (p < 0.01) increase in the abundance of the outbreak-associated carbapenem-resistance plasmid in urban metagenomes between 2016 and 2017. B Linear regression showing a positive and statistically significant correlation between the abundance of the outbreak-associated carbapenem-resistance plasmid and the K. pneumoniae ST-11 chromosome in urban metagenomes. C Linear regression showing a statistically significant and negative correlation between the abundance of the outbreak-associated carbapenem-resistance plasmid in each urban sampling point and the surrounding sewage infrastructure as measured as the density of wastewater collectors(pipes/km2). D Geospatial distribution of sewage collectors (blue dots) and sampling points (red circles) across the city of Montevideo. Size of red circles is proportional to the abundance of the outbreak-associated carbapenem-resistance plasmid

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