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Fig. 4 | Microbiome

Fig. 4

From: Enterotypical Prevotella and three novel bacterial biomarkers in preoperative stool predict the clinical outcome of colorectal cancer

Fig. 4

Metagenome inference of microbial pathways. A Screening prognosis-associated metagenome pathways using PICRUSt2. Wilcoxon test was performed to examine the distribution of microbial pathways. Differential TRFA was regarded as the effect size. B TRFA and taxonomic contribution of pathways enriched in the M5-low patients. C TRFA and taxonomic contribution of pathways depleted in the M5-low patients. D, E PFS curves by thiamine diphosphate salvage II pathway (PWY-6897) (D) and L-histidine degradation pathway (HISDEG-PWY) (E). F TRFA of the two significant microbial pathways by clinical stage and recurrence of CRC. G Spearman’s correlation between TRFA and the number of CD8+ T cells in the epithelium and its significance. The numbers at risk are presented under the survival curves

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Microbiome

ISSN: 2049-2618

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