Fig. 2

RhCMV-infected animals had significantly decreased abundance of bacteria from the order Clostridia. A Differentially abundant bacterial genera analyzed using the limma-voom pipeline with P < 0.05 (*adjusted P < 0.1). B Features selected by elastic-net regression to differentiate between RhCMV− and RhCMV+ animals. C PCA plot generated using log-transformed counts of genera selected by elastic net within the training set. D ROC curve to assess the robustness of elastic-net output. E Summary score for each animal generated by the elastic net. F PCA plot generated using log-transformed counts of genera selected by elastic-net within the testing set (RhCMV-vectored vaccine recipients)