Fig. 3

C. semilaevis intestinal microbial community composition, diversity, and co-occurrence network. A Microbial community compositions in resistant and susceptible families. Unweighted paired-group method with arithmetic means (UPGMA)-based hierarchical clustering (Bray-Curtis distance) was used to cluster the samples according to the microbial community structure. B Venn plot illustrated the shared microbes and specific microbes of resistant and susceptible families. C Shannon index-based microbial diversity. Wilcoxon test was used to detect the variation between resistant and susceptible families. “*”p < 0.1. D Microbial co-occurrence network of resistant and susceptible families. The co-occurrence network is built based on the microbes with relative abundance ≥ 1.00% and coverage of > 10% samples using the Jaccard coefficient as the distance measurement. Only the Jaccard coefficient with an absolute value ≥ 0.6 and p < 0.05 was considered as significant correlations and was visualized in the network. Purple edges indicate positive associations, whereas blue edges reflect negative associations. The size of the nodes indicates the relative abundance of the microbes. The nodes are divided into two portions according to the relative abundance of microbes between resistant and susceptible families (orange portion: resistant family-enriched microbes; green portion: susceptible family-enriched microbes). All of the microbes shown in this figure are based on microbial taxonomical information at the genus level