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Fig. 2 | Microbiome

Fig. 2

From: Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression

Fig. 2

L-LDH relative abundance in the FRT is associated with expression of epithelial junction proteins. Unsupervised hierarchical clustering of intensity-based absolute quantification (iBAQ) values for epithelial barrier-related proteins that were found to be differentially abundant between women (n = 113) with levels of L-LDH protein above (high, purple) or below (low, yellow) the median value for the cohort. The moderated t-test (limma package, R) was used to identify proteins significantly associated with L-LDH relative abundance following false discovery rate adjustment for multiple comparisons. *Proteins that remained significantly associated with L-LDH after adjusting for Lactobacillus relative abundance, as well as the presence of sexually transmitted infections, contraceptive use, and detection of prostate-specific antigen

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Microbiome

ISSN: 2049-2618

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