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Fig. 2 | Microbiome

Fig. 2

From: Gut-derived metabolites influence neurodevelopmental gene expression and Wnt signaling events in a germ-free zebrafish model

Fig. 2

Microbes are both necessary and sufficient for general gene expression in the developing nervous system. A Volcano plot comparing DEGs between germ-free larvae and conventionally raised larvae. B Principal component (PC) analysis of count data from CV, GF, and ZM zebrafish larvae at 2dpf. Numbers 1, 2, and 3 represent the biological replicates. C Heatmap of top 1000 differentially expressed genes between 3 biological replicates of CV, GF, and GF treated with zebrafish gut metabolites (ZM) embryos at 2dpf. Generated with DeSeq2 and ComplexHeatmap

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Microbiome

ISSN: 2049-2618

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