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Fig. 8 | Microbiome

Fig. 8

From: TLR4 regulates RORγt+ regulatory T-cell responses and susceptibility to colon inflammation through interaction with Akkermansia muciniphila

Fig. 8

Mitigated colitis and increased frequency of RORγt+ Treg cells in BMT chimeras following A. muciniphila incubation. a BMT chimeras were incubated with A. muciniphila for 21 days before 2.5% DSS administration. b DAI score. c Representative pictures of colon gross appearance. d Colon length. e Representative flow cytometric analysis of colonic RORγt+ Treg cells among BMT chimeras following A. muciniphila incubation. f Statistical analysis of CD4(+) Foxp3(+) RORγt(+) T cells frequency. a–f n = 6 mice per group, mean values ± SEM are presented, and p-values were calculated using two-way analysis of ANOVA test, *p < 0.05, **p < 0.01, ***p < 0.001. Data are pooled from three independent experiments

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Microbiome

ISSN: 2049-2618

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