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Fig. 1 | Microbiome

Fig. 1

From: Transplantation of bacteriophages from ulcerative colitis patients shifts the gut bacteriome and exacerbates the severity of DSS colitis

Fig. 1

Schematic and timeline of the experimental model. A HMA mice administered healthy or UC bacterial communities were given a single dose of healthy or UC VLPs, followed by 2% DSS. B UC-HMA mice were given four doses of healthy VLPs, UC VLPs, or PBS, followed by 2% DSS. C UC-HMA or GF mice were given four doses of UC VLPs or heat-killed UC VLPs. All groups were then given 2% DSS, except one group of UC-HMA mice given UC VLPs. Each treatment group included 5 or 6 GF or HMA mice per experiment housed in three separate cages. In each experiment 200 μL of bacterial and VLP communities were administered to mice by oral gavage at equal concentrations (1–3 × 108 VLPs or bacterial cells/mL)

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Microbiome

ISSN: 2049-2618

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