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Fig. 4 | Microbiome

Fig. 4

From: Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity

Fig. 4

Modulation of the gut microbiome by RYGB surgery, RYGB microbiota transfer (FMTRYGB) and RYGB microbiota deletion (RYGB(ABx)) in HFD-induced obesity (DIO). a–c Non-metric multidimensional scaling (NMDS) dissimilarity analysis of 16S rRNA gene profiling data, alpha diversity, and richness based on amplicon sequence variant (ASV)-count (a). Mean relative abundance of bacterial families and phyla (A = Actinobacteria, B = Bacteroidetes, F = Firmicutes, P = Proteobacteria, T = Tenericutes, V = Verrumicrobiota) (b). Significantly altered Taxa (c). Distribution and hierarchical clustering of microbial genera (d). Heatmap of portal vein plasma metabolites of respective groups (e). n = 6–10 animals per group with pooled data from 3 independent experiments; *P < 0.05, ** P < 0.01, *** P < 0.001

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Microbiome

ISSN: 2049-2618

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